Supernumerary marker chromosome 15 in a male with azoospermia and open bite deformity
نویسندگان
چکیده
منابع مشابه
Male Infertility Associated with a Supernumerary Marker Chromosome
A marker chromosome (mar) is a structurally abnormal chromosome in which no part can be identified. The significance of a marker varies, depending on the material contained within the marker. Very few reports have been published of marker chromosomes associated with male infertility. Here, we report the case of an infertile man with a rare variant of a marker chromosome of a mos 47,XY,+mar[25]/...
متن کاملSperm analyses, genetic counselling and therapy in an infertile carrier of a supernumerary marker chromosome 15.
PURPOSE A supernumerary marker chromosome (SMC) was analysed after lymphocyte culture of a patient with oligoasthenoteratozoospermia (OAT) before ICSI treatment. MATERIAL AND METHODS By additional molecular cytogenetic investigations the marker could be identified as a heterochromatic derivate of chromosome 15 [karyotype: 47,XY,+der(15)]. RESULTS Sperm analyses by interphase FISH showed a n...
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there is a number of syndromes, associated with proptosis, micrognathia, low-set ear and chest deformity. herein, we report a 9-year-old female with such phenotype who was presented with a vaginal neuroma. the result of karyotype showed 47xx, with extra marker chromosome 22. although such a manifestation had not been reported in the literature, it should be considered as a very rare manifestati...
متن کاملThe First Case of a Small Supernumerary Marker Chromosome 18 in a Klinefelter Fetus: A Case Report
Small supernumerary marker chromosomes (sSMCs), or markers, are abnormal chromosomal fragments that can be hereditary or de novo. Despite the importance of sSMCs diagnosis, de novo sSMCs are rarely detected during the prenatal diagnosis process. Usually, prenatally diagnosed de novo sSMCs cannot be correlated with a particular phenotype without knowing their chromosomal origin and content; ther...
متن کاملnewborn with supernumerary marker chromosome derived from chromosomes 11 and 22- a case report
the interpretation of supernumerary chromosome is important for genetic counseling and prognosis. here, we used snp array and conventional karyotyping method to identify a denovo marker chromosome originated from chromosome 22 and 11 in a newborn transferred to the neonatal intensive care unit of shahid sadoughi hospital in 2015. clinical abnormalities identified in the newborn were dysmorphic...
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ژورنال
عنوان ژورنال: Asian Journal of Andrology
سال: 2009
ISSN: 1008-682X,1745-7262
DOI: 10.1038/aja.2009.37